Rheological Influence Upon the Glomerular Podocyte and Resultant Mechanotransduction
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چکیده
منابع مشابه
Effect of Ultrasound Assisted Extraction upon the Protein Content and Rheological Properties of the Resultant Soymilk
The purpose of this study was to determine the effect of ultrasound treatment on the protein content and rheological properties of soymilk extracted from soybeans. Soybean slurry was exposed to ultrasound treatment then filtered. In this work, an ultrasound cleaning bath set with 35 kHz frequency and different treatment temperatures (20 and 40oC) and times (20, 40, and 60 min) was used. Results...
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The renal glomerulus, the site of plasma ultrafiltration and the production of primary urine (1), is the locus of a number of progressive disorders that lead to chronic renal insufficiency. Before the advent of renal replacement therapies, these diseases invariably led to death by uremia. Still, while these treatments save, or at least extend, patient’s lives, they do so at an enormous price, b...
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Glomerular podocytes are highly specialized cells with a complex cytoarchitecture. Their most prominent features are interdigitated foot processes with filtration slits in between. These are bridged by the slit diaphragm, which plays a major role in establishing the selective permeability of the glomerular filtration barrier. Injury to podocytes leads to proteinuria, a hallmark of most glomerul...
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The podocyte is the most differentiated cell type in the glomerulum, which forms a crucial component of the glomerular filtration barrier. It has been assumed that podocyte foot processes counteract the elastic force of the glomerular basement membrane and that vasoactive hormones may regulate the contractile state of their foot processes and thereby modulate the ultrafiltration coefficient K(f...
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s Nephron 2016;132:245–291 DOI: 10.1159/000445271 257 ing childhood NS. Moreover, reductions in glomerular and podocyte SULF2 expression also corresponded with injury, while glucocorticoid treatment restored SULF2 in podocytes. Our data suggest that SULF2 plays an important role in glucocorticoid response in NS.
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ژورنال
عنوان ژورنال: Kidney and Blood Pressure Research
سال: 2015
ISSN: 1420-4096,1423-0143
DOI: 10.1159/000368493